| Reaction Details |
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 | Report a problem with these data |
| Target | Alkaline phosphatase, tissue-nonspecific isozyme |
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| Ligand | BDBM39585 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SAR assay for compounds activating TNAP in the presence of 100 mM DEA performed in a luminescence assay |
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| EC50 | 12100±n/a nM |
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| Citation |  PubChem, PC SAR assay for compounds activating TNAP in the presence of 100 mM DEA performed in a luminescence assay PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Alkaline phosphatase, tissue-nonspecific isozyme |
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| Name: | Alkaline phosphatase, tissue-nonspecific isozyme |
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| Synonyms: | ALPL | PPBT_HUMAN | tissue-nonspecific alkaline phosphatase precursor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57306.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1448917 |
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| Residue: | 524 |
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| Sequence: | MISPFLVLAIGTCLTNSLVPEKEKDPKYWRDQAQETLKYALELQKLNTNVAKNVIMFLGD
GMGVSTVTAARILKGQLHHNPGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCG
VKANEGTVGVSAATERSRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAH
SADRDWYSDNEMPPEALSQGCKDIAYQLMHNIRDIDVIMGGGRKYMYPKNKTDVEYESDE
KARGTRLDGLDLVDTWKSFKPRYKHSHFIWNRTELLTLDPHNVDYLLGLFEPGDMQYELN
RNNVTDPSLSEMVVVAIQILRKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDRAIG
QAGSLTSSEDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMLSDTDKKPFTAILYGNGPG
YKVVGGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFSKGPMAHLLHGVHEQNYV
PHVMAYAACIGANLGHCAPASSAGSLAAGPLLLALALYPLSVLF
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|
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| BDBM39585 |
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| n/a |
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| Name | BDBM39585 |
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| Synonyms: | 5-(4-methoxyphenyl)-N-(2-pyridinylmethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine | 5-(4-methoxyphenyl)-N-(pyridin-2-ylmethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine | MLS000034811 | SMR000000772 | [5-(4-Methoxy-phenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]-pyridin-2-ylmethyl-amine | [5-(4-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]-(2-pyridylmethyl)amine | cid_655783 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H16N6O |
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| Mol. Mass. | 332.3592 |
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| SMILES | COc1ccc(cc1)-c1cc(NCc2ccccn2)n2ncnc2n1 |
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| Structure | 
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