| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alkaline phosphatase, tissue-nonspecific isozyme |
|---|
| Ligand | BDBM43809 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | SAR assay for compounds activating TNAP in the presence of 100 mM DEA performed in a luminescence assay |
|---|
| EC50 | 10300±n/a nM |
|---|
| Citation |  PubChem, PC SAR assay for compounds activating TNAP in the presence of 100 mM DEA performed in a luminescence assay PubChem Bioassay(2009)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Alkaline phosphatase, tissue-nonspecific isozyme |
|---|
| Name: | Alkaline phosphatase, tissue-nonspecific isozyme |
|---|
| Synonyms: | ALPL | PPBT_HUMAN | tissue-nonspecific alkaline phosphatase precursor |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 57306.17 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1448917 |
|---|
| Residue: | 524 |
|---|
| Sequence: | MISPFLVLAIGTCLTNSLVPEKEKDPKYWRDQAQETLKYALELQKLNTNVAKNVIMFLGD
GMGVSTVTAARILKGQLHHNPGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCG
VKANEGTVGVSAATERSRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAH
SADRDWYSDNEMPPEALSQGCKDIAYQLMHNIRDIDVIMGGGRKYMYPKNKTDVEYESDE
KARGTRLDGLDLVDTWKSFKPRYKHSHFIWNRTELLTLDPHNVDYLLGLFEPGDMQYELN
RNNVTDPSLSEMVVVAIQILRKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDRAIG
QAGSLTSSEDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMLSDTDKKPFTAILYGNGPG
YKVVGGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFSKGPMAHLLHGVHEQNYV
PHVMAYAACIGANLGHCAPASSAGSLAAGPLLLALALYPLSVLF
|
|
|
|---|
| BDBM43809 |
|---|
| n/a |
|---|
| Name | BDBM43809 |
|---|
| Synonyms: | 1-[(2-cyclopropylquinolin-4-yl)carbonylamino]-3-ethyl-thiourea | 1-[(2-cyclopropylquinoline-4-carbonyl)amino]-3-ethyl-thiourea | 1-[(2-cyclopropylquinoline-4-carbonyl)amino]-3-ethylthiourea | 1-[[(2-cyclopropyl-4-quinolinyl)-oxomethyl]amino]-3-ethylthiourea | MLS-0097197.0001 | cid_1767496 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H18N4OS |
|---|
| Mol. Mass. | 314.405 |
|---|
| SMILES | CCNC(=S)NNC(=O)c1cc(nc2ccccc12)C1CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
