Ki Summary

Reaction Details

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Target

Beta-lactamase

Ligand

BDBM51948

Substrate/Competitor

n/a

Meas. Tech.

FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts.

IC50

941±n/a nM

Citation

PubChem, PC FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts. PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Beta-lactamase

Name:

Beta-lactamase

Synonyms:

Beta lactamase

Type:

Enzyme Catalytic Domain

Mol. Mass.:

31513.38

Organism:

Pseudomonas aeruginosa

Description:

gi_114881106

Residue:

286

Sequence:

MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRP
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW

BDBM51948

n/a

Name

BDBM51948

Synonyms:

(4Z)-4-[(4-fluorophenyl)-hydroxy-methylene]-5-(2-pyridyl)-1-(3-pyridylmethyl)pyrrolidine-2,3-quinone | (4Z)-4-[(4-fluorophenyl)-hydroxymethylidene]-5-(2-pyridinyl)-1-(3-pyridinylmethyl)pyrrolidine-2,3-dione | (4Z)-4-[(4-fluorophenyl)-hydroxymethylidene]-5-pyridin-2-yl-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione | (4Z)-4-[(4-fluorophenyl)-oxidanyl-methylidene]-5-pyridin-2-yl-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione | MLS000037253 | SMR000042455 | cid_5389373

Type

Small organic molecule

Emp. Form.

C22H16FN3O3

Mol. Mass.

389.3791

SMILES

Fc1ccc(cc1)C(=O)C1C(N(Cc2cccnc2)C(=O)C1=O)c1ccccn1

Structure