Ki Summary

Reaction Details

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Target

Beta-lactamase

Ligand

BDBM51975

Substrate/Competitor

n/a

Meas. Tech.

FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts.

IC50

2742±n/a nM

Citation

PubChem, PC FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts. PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Beta-lactamase

Name:

Beta-lactamase

Synonyms:

Beta lactamase

Type:

Enzyme Catalytic Domain

Mol. Mass.:

31513.38

Organism:

Pseudomonas aeruginosa

Description:

gi_114881106

Residue:

286

Sequence:

MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRP
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW

BDBM51975

n/a

Name

BDBM51975

Synonyms:

6-(2-methylpropyl)-4-[1-(6-methylpyridin-2-yl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carbonyl]-1H-pyrimidin-2-one | 6-(2-methylpropyl)-4-[[1-(6-methyl-2-pyridinyl)-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]-oxomethyl]-1H-pyrimidin-2-one | 6-(2-methylpropyl)-4-[[1-(6-methylpyridin-2-yl)-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]carbonyl]-1H-pyrimidin-2-one | 6-isobutyl-4-[1-(6-methyl-2-pyridyl)-1,3,4,9-tetrahydro-beta-carboline-2-carbonyl]-1H-pyrimidin-2-one | 6-isobutyl-4-{[1-(6-methylpyridin-2-yl)-1,3,4,9-tetrahydro-2H-beta-carbolin-2-yl]carbonyl}pyrimidin-2(1H)-one | MLS000862704 | SMR000319578 | cid_16187921

Type

Small organic molecule

Emp. Form.

C26H27N5O2

Mol. Mass.

441.5249

SMILES

CC(C)Cc1cc([nH]c(=O)n1)C(=O)N1CCc2c([nH]c3ccccc23)C1c1cccc(C)n1

Structure