| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-lactamase |
|---|
| Ligand | BDBM51954 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase. |
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| IC50 | 59640±n/a nM |
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| Citation |  PubChem, PC FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase. PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
|---|
| Synonyms: | Beta-lactamase | metallo-beta-lactamase IMP-1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 27125.88 |
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| Organism: | Pseudomonas aeruginosa |
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| Description: | gi_27368096 |
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| Residue: | 246 |
|---|
| Sequence: | MSKLSVFFIFLFCSIATAAESLPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNA
EAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELT
NELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKP
YGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESKK
PSKPSN
|
|
|
|---|
| BDBM51954 |
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| n/a |
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| Name | BDBM51954 |
|---|
| Synonyms: | (2-benzoyl-1H-pyrrol-1-yl)acetic acid | 2-(2-benzoyl-1-pyrrolyl)acetic acid | 2-(2-benzoylpyrrol-1-yl)acetic acid | 2-[2-(phenylcarbonyl)pyrrol-1-yl]ethanoic acid | CHEMBL335619 | MLS000095834 | SMR000031382 | cid_3239785 |
|---|
| Type | Small organic molecule |
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| Emp. Form. | C13H11NO3 |
|---|
| Mol. Mass. | 229.2313 |
|---|
| SMILES | OC(=O)Cn1cccc1C(=O)c1ccccc1 |
|---|
| Structure | 
|
|---|
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