| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM51959 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase. |
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| IC50 | 59640±n/a nM |
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| Citation |  PubChem, PC FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase. PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | Beta-lactamase | metallo-beta-lactamase IMP-1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 27125.88 |
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| Organism: | Pseudomonas aeruginosa |
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| Description: | gi_27368096 |
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| Residue: | 246 |
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| Sequence: | MSKLSVFFIFLFCSIATAAESLPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNA
EAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELT
NELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKP
YGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESKK
PSKPSN
|
|
|
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| BDBM51959 |
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| n/a |
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| Name | BDBM51959 |
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| Synonyms: | 4-butyl-3-(2-methyl-3-furanyl)-1H-1,2,4-triazole-5-thione | 4-butyl-3-(2-methyl-3-furyl)-1H-1,2,4-triazole-5-thione | 4-butyl-3-(2-methylfuran-3-yl)-1H-1,2,4-triazole-5-thione | 4-butyl-5-(2-methyl-3-furyl)-4H-1,2,4-triazole-3-thiol | MLS000547853 | SMR000115049 | cid_1768039 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H15N3OS |
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| Mol. Mass. | 237.321 |
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| SMILES | CCCCn1c(n[nH]c1=S)-c1ccoc1C |
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| Structure | 
|
|---|
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