Reaction Details |
| Report a problem with these data |
Target | Beta-lactamase |
---|
Ligand | BDBM51962 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase. |
---|
IC50 | 59640±n/a nM |
---|
Citation | PubChem, PC FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase. PubChem Bioassay(2009)[AID] |
---|
More Info.: | Get all data from this article, Solution Info, Assay Method |
---|
|
Beta-lactamase |
---|
Name: | Beta-lactamase |
Synonyms: | Beta-lactamase | metallo-beta-lactamase IMP-1 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 27125.88 |
Organism: | Pseudomonas aeruginosa |
Description: | gi_27368096 |
Residue: | 246 |
Sequence: | MSKLSVFFIFLFCSIATAAESLPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNA
EAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELT
NELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKP
YGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESKK
PSKPSN
|
|
|
BDBM51962 |
---|
n/a |
---|
Name | BDBM51962 |
Synonyms: | 4-butyl-3-(4-chloranyl-1,5-dimethyl-pyrazol-3-yl)-1H-1,2,4-triazole-5-thione | 4-butyl-3-(4-chloro-1,5-dimethyl-3-pyrazolyl)-1H-1,2,4-triazole-5-thione | 4-butyl-3-(4-chloro-1,5-dimethyl-pyrazol-3-yl)-1H-1,2,4-triazole-5-thione | 4-butyl-3-(4-chloro-1,5-dimethylpyrazol-3-yl)-1H-1,2,4-triazole-5-thione | MLS000519348 | SMR000129767 | cid_3331652 |
Type | Small organic molecule |
Emp. Form. | C11H16ClN5S |
Mol. Mass. | 285.796 |
SMILES | CCCCn1c(n[nH]c1=S)-c1nn(C)c(C)c1Cl |
Structure |
|