| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-lactamase |
|---|
| Ligand | BDBM52007 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase. |
|---|
| IC50 | 59640±n/a nM |
|---|
| Citation |  PubChem, PC FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase. PubChem Bioassay(2009)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Beta-lactamase |
|---|
| Name: | Beta-lactamase |
|---|
| Synonyms: | Beta-lactamase | metallo-beta-lactamase IMP-1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 27125.88 |
|---|
| Organism: | Pseudomonas aeruginosa |
|---|
| Description: | gi_27368096 |
|---|
| Residue: | 246 |
|---|
| Sequence: | MSKLSVFFIFLFCSIATAAESLPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNA
EAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELT
NELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKP
YGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESKK
PSKPSN
|
|
|
|---|
| BDBM52007 |
|---|
| n/a |
|---|
| Name | BDBM52007 |
|---|
| Synonyms: | (5-nitro-2-phenyl-phenyl)arsonic acid | (5-nitro-2-phenylphenyl)arsonic acid | MLS000756422 | SMR000528721 | cid_302501 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H10AsNO5 |
|---|
| Mol. Mass. | 323.1331 |
|---|
| SMILES | O[As](O)(=O)c1cc(ccc1-c1ccccc1)[N+]([O-])=O |
|---|
| Structure | 
|
|---|
Search and Browse
