BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetPOsterior Segregation
LigandBDBM52845
Substrate/Competitorn/a
Meas. Tech.Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50 7637±n/a nM
Citation PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay(2009)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
POsterior Segregation
Name:POsterior Segregation
Synonyms:POsterior Segregation family member (pos-1)
Type:Enzyme Catalytic Domain
Mol. Mass.:29838.90
Organism:Caenorhabditis elegans
Description:gi_17562800
Residue:264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKET
QNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCR
FAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGA
HANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYN
STAQLAQYFESQFQRIQQLSSHHH
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM52845
n/a
NameBDBM52845
Synonyms:(3Z)-3-[2-keto-2-(p-tolyl)ethylidene]-6-methyl-4H-1,4-benzoxazin-2-one | (3Z)-6-methyl-3-[2-(4-methylphenyl)-2-oxidanylidene-ethylidene]-4H-1,4-benzoxazin-2-one | (3Z)-6-methyl-3-[2-(4-methylphenyl)-2-oxoethylidene]-4H-1,4-benzoxazin-2-one | 6-Methyl-3-[2-oxo-2-p-tolyl-eth-(E)-ylidene]-3,4-dihydro-benzo[1,4]oxazin-2-one | MLS000768944 | SMR000433678 | cid_5587444
TypeSmall organic molecule
Emp. Form.C18H15NO3
Mol. Mass.293.3166
SMILESCc1ccc(cc1)C(=O)Cc1nc2cc(C)ccc2oc1=O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: