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TargetTyrosine-protein phosphatase non-receptor type 7
LigandBDBM53492
Substrate/Competitorn/a
Meas. Tech.HTS Discovery of Chemical Inhibitors of HePTP, a Leukemia Target
IC50 4660±n/a nM
Citation PubChem, PC HTS Discovery of Chemical Inhibitors of HePTP, a Leukemia Target PubChem Bioassay(2008)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Tyrosine-protein phosphatase non-receptor type 7
Name:Tyrosine-protein phosphatase non-receptor type 7
Synonyms:He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:Protein
Mol. Mass.:40530.79
Organism:Homo sapiens (Human)
Description:P35236
Residue:360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP
ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA
SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW
EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY
QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC
FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
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BDBM53492
n/a
NameBDBM53492
Synonyms:6-[4-(4-fluorophenyl)piperazin-1-yl]sulfonyl-4-oxidanylidene-1H-quinoline-3-carboxylic acid | 6-[4-(4-fluorophenyl)piperazin-1-yl]sulfonyl-4-oxo-1H-quinoline-3-carboxylic acid | 6-[4-(4-fluorophenyl)piperazino]sulfonyl-4-keto-1H-quinoline-3-carboxylic acid | 6-[[4-(4-fluorophenyl)-1-piperazinyl]sulfonyl]-4-oxo-1H-quinoline-3-carboxylic acid | 6-{[4-(4-fluorophenyl)piperazin-1-yl]sulfonyl}-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | MLS000095701 | SMR000031249 | cid_3237353
TypeSmall organic molecule
Emp. Form.C20H18FN3O5S
Mol. Mass.431.437
SMILESOC(=O)c1cnc2ccc(cc2c1O)S(=O)(=O)N1CCN(CC1)c1ccc(F)cc1
Structure
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