| Reaction Details |
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 | Report a problem with these data |
| Target | Mannose-6-phosphate isomerase |
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| Ligand | BDBM53393 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay. |
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| IC50 | 4500.9±n/a nM |
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| Citation |  PubChem, PC HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay. PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Mannose-6-phosphate isomerase |
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| Name: | Mannose-6-phosphate isomerase |
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| Synonyms: | MPI | MPI protein | MPI_HUMAN | Mannose-6-phosphate isomerase | PMI1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46651.35 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1448919 |
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| Residue: | 423 |
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| Sequence: | MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAK
ILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEK
LHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLK
QTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQ
LHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTP
KFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYK
VLALDSASILLMVQGTVIASTPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRAC
CLL
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| BDBM53393 |
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| n/a |
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| Name | BDBM53393 |
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| Synonyms: | 3,4,5-trihydroxy-N'-{(1E)-[3-hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl]methylene}benzohydrazide | 5-hydroxy-N'-[(Z)-(3-hydroxy-2-methyl-5-methylol-1H-pyridin-4-ylidene)methyl]-3,4-diketo-cyclohexa-1,5-diene-1-carbohydrazide | 5-hydroxy-N'-[(Z)-[3-hydroxy-5-(hydroxymethyl)-2-methyl-1H-pyridin-4-ylidene]methyl]-3,4-dioxo-1-cyclohexa-1,5-dienecarbohydrazide | 5-hydroxy-N'-[(Z)-[3-hydroxy-5-(hydroxymethyl)-2-methyl-1H-pyridin-4-ylidene]methyl]-3,4-dioxocyclohexa-1,5-diene-1-carbohydrazide | MLS000673322 | N'-[(Z)-[5-(hydroxymethyl)-2-methyl-3-oxidanyl-1H-pyridin-4-ylidene]methyl]-5-oxidanyl-3,4-bis(oxidanylidene)cyclohexa-1,5-diene-1-carbohydrazide | SMR000314563 | cid_6251022 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H15N3O6 |
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| Mol. Mass. | 333.2961 |
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| SMILES | Cc1ncc(CO)c(CNNC(=O)C2=CC(=O)C(=O)C(=O)C2)c1O |t:13| |
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| Structure | 
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