| Reaction Details |
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 | Report a problem with these data |
| Target | Mannose-6-phosphate isomerase |
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| Ligand | BDBM34977 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay. |
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| IC50 | 5361.1±n/a nM |
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| Citation |  PubChem, PC HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay. PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Mannose-6-phosphate isomerase |
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| Name: | Mannose-6-phosphate isomerase |
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| Synonyms: | MPI | MPI protein | MPI_HUMAN | Mannose-6-phosphate isomerase | PMI1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46651.35 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1448919 |
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| Residue: | 423 |
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| Sequence: | MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAK
ILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEK
LHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLK
QTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQ
LHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTP
KFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYK
VLALDSASILLMVQGTVIASTPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRAC
CLL
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| BDBM34977 |
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| n/a |
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| Name | BDBM34977 |
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| Synonyms: | (4Z)-4-[(2-hydroxyethylamino)methylene]-5-keto-2-methyl-benzo[g]benzofuran-3-carboxylic acid ethyl ester | (4Z)-4-[(2-hydroxyethylamino)methylidene]-2-methyl-5-oxo-3-benzo[g]benzofurancarboxylic acid ethyl ester | MLS000761560 | SMR000371659 | cid_5546403 | ethyl (4Z)-4-[(2-hydroxyethylamino)methylidene]-2-methyl-5-oxidanylidene-benzo[g][1]benzofuran-3-carboxylate | ethyl (4Z)-4-[(2-hydroxyethylamino)methylidene]-2-methyl-5-oxobenzo[g][1]benzofuran-3-carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C19H19NO5 |
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| Mol. Mass. | 341.3579 |
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| SMILES | CCOC(=O)c1c(C)oc2c1c(C=NCCO)c(O)c1ccccc21 |w:13.14| |
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| Structure | 
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