| Reaction Details |
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 | Report a problem with these data |
| Target | GTPase KRas [1-37] |
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| Ligand | BDBM54558 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant |
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| EC50 | 30000±n/a nM |
|---|
| Citation |  PubChem, PC Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| GTPase KRas [1-37] |
|---|
| Name: | GTPase KRas [1-37] |
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| Synonyms: | ras protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 4034.04 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_190938 |
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| Residue: | 37 |
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| Sequence: | MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIE
|
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|
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| BDBM54558 |
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| n/a |
|---|
| Name | BDBM54558 |
|---|
| Synonyms: | 1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-2-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]ethanone | 1-[4-(2,5-dimethylphenyl)piperazin-1-yl]-2-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]ethanone | 1-[4-(2,5-dimethylphenyl)piperazino]-2-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]ethanone | KUC103369N | UNM-0000306079 | cid_20900764 |
|---|
| Type | Small organic molecule |
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| Emp. Form. | C23H26N4O3 |
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| Mol. Mass. | 406.4775 |
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| SMILES | COc1ccc(cc1)-c1noc(CC(=O)N2CCN(CC2)c2cc(C)ccc2C)n1 |
|---|
| Structure | 
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|---|
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