| Reaction Details |
|---|
 | Report a problem with these data |
| Target | GTPase KRas [1-37] |
|---|
| Ligand | BDBM54687 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant |
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| EC50 | 30000±n/a nM |
|---|
| Comments | Extracted from aid = 2043 and tid = 2 |
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| Citation |  PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| GTPase KRas [1-37] |
|---|
| Name: | GTPase KRas [1-37] |
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| Synonyms: | ras protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 4034.04 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_190938 |
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| Residue: | 37 |
|---|
| Sequence: | MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIE
|
|
|
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| BDBM54687 |
|---|
| n/a |
|---|
| Name | BDBM54687 |
|---|
| Synonyms: | 2-amino-5-benzoyl-1-butylsulfonyl-4-(3,4,5-trimethoxyphenyl)-3-pyrrolecarbonitrile | 2-amino-5-benzoyl-1-butylsulfonyl-4-(3,4,5-trimethoxyphenyl)pyrrole-3-carbonitrile | 2-azanyl-1-butylsulfonyl-5-(phenylcarbonyl)-4-(3,4,5-trimethoxyphenyl)pyrrole-3-carbonitrile | UNM-0000305777 | cid_25220928 |
|---|
| Type | Small organic molecule |
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| Emp. Form. | C25H27N3O6S |
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| Mol. Mass. | 497.563 |
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| SMILES | CCCCS(=O)(=O)n1c(N)c(C#N)c(c1C(=O)c1ccccc1)-c1cc(OC)c(OC)c(OC)c1 |
|---|
| Structure | 
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|---|
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