| Reaction Details |
|---|
 | Report a problem with these data |
| Target | GTPase KRas [1-37] |
|---|
| Ligand | BDBM54699 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant |
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| EC50 | 30000±n/a nM |
|---|
| Comments | Extracted from aid = 2043 and tid = 2 |
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| Citation |  PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| GTPase KRas [1-37] |
|---|
| Name: | GTPase KRas [1-37] |
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| Synonyms: | ras protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 4034.04 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_190938 |
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| Residue: | 37 |
|---|
| Sequence: | MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIE
|
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|
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| BDBM54699 |
|---|
| n/a |
|---|
| Name | BDBM54699 |
|---|
| Synonyms: | 4-(1-oxo-3-phenylprop-2-ynyl)benzonitrile | 4-(3-phenylprop-2-ynoyl)benzenecarbonitrile | 4-(3-phenylprop-2-ynoyl)benzonitrile | 4-(3-phenylpropioloyl)benzonitrile | UNM-0000306057 | cid_11708441 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H9NO |
|---|
| Mol. Mass. | 231.2488 |
|---|
| SMILES | O=C(C#Cc1ccccc1)c1ccc(cc1)C#N |
|---|
| Structure | 
|
|---|
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