| Reaction Details |
|---|
 | Report a problem with these data |
| Target | GTPase KRas [1-37] |
|---|
| Ligand | BDBM54623 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant |
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| EC50 | 30000±n/a nM |
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| Citation |  PubChem, PC Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| GTPase KRas [1-37] |
|---|
| Name: | GTPase KRas [1-37] |
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| Synonyms: | ras protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 4034.04 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_190938 |
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| Residue: | 37 |
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| Sequence: | MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIE
|
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|
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| BDBM54623 |
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| n/a |
|---|
| Name | BDBM54623 |
|---|
| Synonyms: | 1-(2,5-dichlorophenyl)-3-(4-fluorophenyl)-5-(4-methoxyphenyl)-2-pyrazoline | 2-(2,5-dichlorophenyl)-5-(4-fluorophenyl)-3-(4-methoxyphenyl)-3,4-dihydropyrazole | 2-[2,5-bis(chloranyl)phenyl]-5-(4-fluorophenyl)-3-(4-methoxyphenyl)-3,4-dihydropyrazole | UNM-0000305862 | cid_25227385 |
|---|
| Type | Small organic molecule |
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| Emp. Form. | C22H17Cl2FN2O |
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| Mol. Mass. | 415.288 |
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| SMILES | COc1ccc(cc1)C1CC(=NN1c1cc(Cl)ccc1Cl)c1ccc(F)cc1 |c:11| |
|---|
| Structure | 
|
|---|
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