Reaction Details |
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Target | GTPase KRas [1-37] |
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Ligand | BDBM54626 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant |
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EC50 | 30000±n/a nM |
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Citation | PubChem, PC Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant PubChem Bioassay(2009)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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GTPase KRas [1-37] |
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Name: | GTPase KRas [1-37] |
Synonyms: | ras protein |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 4034.04 |
Organism: | Homo sapiens (Human) |
Description: | gi_190938 |
Residue: | 37 |
Sequence: | MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIE
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BDBM54626 |
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n/a |
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Name | BDBM54626 |
Synonyms: | 3-(4-chlorophenyl)-2-(3-fluorophenyl)-5-(4-methoxyphenyl)-3,4-dihydropyrazole | 5-(4-chlorophenyl)-1-(3-fluorophenyl)-3-(4-methoxyphenyl)-2-pyrazoline | UNM-0000305865 | cid_2883157 |
Type | Small organic molecule |
Emp. Form. | C22H18ClFN2O |
Mol. Mass. | 380.843 |
SMILES | COc1ccc(cc1)C1=NN(C(C1)c1ccc(Cl)cc1)c1cccc(F)c1 |t:9| |
Structure |
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