| Reaction Details |
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 | Report a problem with these data |
| Target | GTPase KRas [1-37] |
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| Ligand | BDBM54639 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant |
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| EC50 | 30000±n/a nM |
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| Citation |  PubChem, PC Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| GTPase KRas [1-37] |
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| Name: | GTPase KRas [1-37] |
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| Synonyms: | ras protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 4034.04 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_190938 |
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| Residue: | 37 |
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| Sequence: | MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIE
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| BDBM54639 |
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| n/a |
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| Name | BDBM54639 |
|---|
| Synonyms: | 4-[3-(3-bromophenyl)-5-(4-methoxyphenyl)-2-pyrazolin-1-yl]benzenesulfonamide | 4-[5-(3-bromophenyl)-3-(4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]benzenesulfonamide | KUC103395N | UNM-0000306113 | cid_42628040 |
|---|
| Type | Small organic molecule |
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| Emp. Form. | C22H20BrN3O3S |
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| Mol. Mass. | 486.382 |
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| SMILES | COc1ccc(cc1)C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)c1cccc(Br)c1 |c:11| |
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| Structure | 
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