| Reaction Details |
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 | Report a problem with these data |
| Target | Bcl-2-related protein A1 |
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| Ligand | BDBM33041 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1 |
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| EC50 | 5440±n/a nM |
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| Citation |  PubChem, PC Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1 PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Bcl-2-related protein A1 |
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| Name: | Bcl-2-related protein A1 |
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| Synonyms: | B2LA1_HUMAN | BCL2A1 | BCL2L5 | BFL1 | Bcl-2-like protein 5 | GRS | HBPA1 | Hemopoietic-specific early response protein | Protein BFL-1 | Protein GRS |
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| Type: | Apoptosis regulator protein |
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| Mol. Mass.: | 20130.01 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 175 |
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| Sequence: | MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVN
VVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISY
FVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC
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| BDBM33041 |
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| n/a |
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| Name | BDBM33041 |
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| Synonyms: | 2-amino-6-(5-methyl-2-furanyl)-4-(4-methylphenyl)-3-pyridinecarbonitrile | 2-amino-6-(5-methyl-2-furyl)-4-(p-tolyl)nicotinonitrile | 2-amino-6-(5-methylfuran-2-yl)-4-(4-methylphenyl)pyridine-3-carbonitrile | 2-azanyl-6-(5-methylfuran-2-yl)-4-(4-methylphenyl)pyridine-3-carbonitrile | MLS000079801 | SMR000037643 | cid_661059 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H15N3O |
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| Mol. Mass. | 289.3312 |
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| SMILES | Cc1ccc(o1)-c1cc(-c2ccc(C)cc2)c(C#N)c(N)n1 |
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| Structure | 
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