Ki Summary

Reaction Details

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Target

Streptokinase A

Ligand

BDBM58064

Substrate/Competitor

n/a

Meas. Tech.

Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression

EC50

150000±n/a nM

Citation

PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Streptokinase A

Name:

Streptokinase A

Synonyms:

STRP_STRP1 | ska | streptokinase A precursor

Type:

Enzyme Catalytic Domain

Mol. Mass.:

49924.80

Organism:

Streptococcus pyogenes M1 GAS

Description:

gi_15675770

Residue:

440

Sequence:

MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVF
INFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSN
DGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQ
AKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGY
TIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKY
YVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAK
LLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEER
KAYSYLRDTGTPIPDNPKDK

BDBM58064

n/a

Name

BDBM58064

Synonyms:

(2S)-2-bromo-N-(2,3-dichlorophenyl)-3-keto-4,7,7-trimethyl-norbornane-1-carboxamide | (3S)-3-bromo-N-(2,3-dichlorophenyl)-1,7,7-trimethyl-2-oxo-4-bicyclo[2.2.1]heptanecarboxamide | (3S)-3-bromo-N-(2,3-dichlorophenyl)-1,7,7-trimethyl-2-oxobicyclo[2.2.1]heptane-4-carboxamide | (3S)-N-[2,3-bis(chloranyl)phenyl]-3-bromanyl-1,7,7-trimethyl-2-oxidanylidene-bicyclo[2.2.1]heptane-4-carboxamide | 2-Bromo-4,7,7-trimethyl-3-oxo-bicyclo[2.2.1]heptane-1-carboxylic acid (2,3-dichloro-phenyl)-amide | MLS000768761 | SMR000432106 | cid_16682217

Type

Small organic molecule

Emp. Form.

C17H18BrCl2NO2

Mol. Mass.

419.14

SMILES

CC1(C)C2(C)CCC1([C@H](Br)C2=O)C(=O)Nc1cccc(Cl)c1Cl |TLB:11:10:1:6.5,THB:9:8:1:6.5|

Structure