| Reaction Details |
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 | Report a problem with these data |
| Target | Nucleotide-binding oligomerization domain-containing protein 1 |
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| Ligand | BDBM54470 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | uHTS luminescence assay for the identification of compounds that inhibit NOD1 |
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| EC50 | 1670±n/a nM |
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| Citation |  PubChem, PC uHTS luminescence assay for the identification of compounds that inhibit NOD1 PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Nucleotide-binding oligomerization domain-containing protein 1 |
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| Name: | Nucleotide-binding oligomerization domain-containing protein 1 |
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| Synonyms: | CARD4 | NOD1 | NOD1_HUMAN | nucleotide-binding oligomerization domain containing 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 107699.03 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_5174617 |
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| Residue: | 953 |
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| Sequence: | MEEQGHSEMEIIPSESHPHIQLLKSNRELLVTHIRNTQCLVDNLLKNDYFSAEDAEIVCA
CPTQPDKVRKILDLVQSKGEEVSEFFLYLLQQLADAYVDLRPWLLEIGFSPSLLTQSKVV
VNTDPVSRYTQQLRHHLGRDSKFVLCYAQKEELLLEEIYMDTIMELVGFSNESLGSLNSL
ACLLDHTTGILNEQGETIFILGDAGVGKSMLLQRLQSLWATGRLDAGVKFFFHFRCRMFS
CFKESDRLCLQDLLFKHYCYPERDPEEVFAFLLRFPHVALFTFDGLDELHSDLDLSRVPD
SSCPWEPAHPLVLLANLLSGKLLKGASKLLTARTGIEVPRQFLRKKVLLRGFSPSHLRAY
ARRMFPERALQDRLLSQLEANPNLCSLCSVPLFCWIIFRCFQHFRAAFEGSPQLPDCTMT
LTDVFLLVTEVHLNRMQPSSLVQRNTRSPVETLHAGRDTLCSLGQVAHRGMEKSLFVFTQ
EEVQASGLQERDMQLGFLRALPELGPGGDQQSYEFFHLTLQAFFTAFFLVLDDRVGTQEL
LRFFQEWMPPAGAATTSCYPPFLPFQCLQGSGPAREDLFKNKDHFQFTNLFLCGLLSKAK
QKLLRHLVPAAALRRKRKALWAHLFSSLRGYLKSLPRVQVESFNQVQAMPTFIWMLRCIY
ETQSQKVGQLAARGICANYLKLTYCNACSADCSALSFVLHHFPKRLALDLDNNNLNDYGV
RELQPCFSRLTVLRLSVNQITDGGVKVLSEELTKYKIVTYLGLYNNQITDVGARYVTKIL
DECKGLTHLKLGKNKITSEGGKYLALAVKNSKSISEVGMWGNQVGDEGAKAFAEALRNHP
SLTTLSLASNGISTEGGKSLARALQQNTSLEILWLTQNELNDEVAESLAEMLKVNQTLKH
LWLIQNQITAKGTAQLADALQSNTGITEICLNGNLIKPEEAKVYEDEKRIICF
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| BDBM54470 |
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| n/a |
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| Name | BDBM54470 |
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| Synonyms: | 1-[2-methyl-5-[4-(4-nitrophenyl)piperazin-1-yl]sulfonyl-2,3-dihydroindol-1-yl]propan-1-one | 1-[2-methyl-5-[4-(4-nitrophenyl)piperazino]sulfonyl-indolin-1-yl]propan-1-one | 1-[2-methyl-5-[[4-(4-nitrophenyl)-1-piperazinyl]sulfonyl]-2,3-dihydroindol-1-yl]-1-propanone | CHEMBL1364793 | MLS000950704 | SMR000622486 | cid_16002787 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H26N4O5S |
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| Mol. Mass. | 458.531 |
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| SMILES | CCC(=O)N1C(C)Cc2cc(ccc12)S(=O)(=O)N1CCN(CC1)c1ccc(cc1)[N+]([O-])=O |
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| Structure | 
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