| Reaction Details |
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 | Report a problem with these data |
| Target | Procathepsin L |
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| Ligand | BDBM56911 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for inhibitors of M1 and M17 aminopeptidases: QFRET-based biochemical high throughput dose response assay for inhibitors of the Cathepsin L proteinase (CTSL1). |
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| IC50 | >59642±n/a nM |
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| Citation |  PubChem, PC Counterscreen for inhibitors of M1 and M17 aminopeptidases: QFRET-based biochemical high throughput dose response assay for inhibitors of the Cathepsin L proteinase (CTSL1). PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Procathepsin L |
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| Name: | Procathepsin L |
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| Synonyms: | CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein |
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| Type: | Enzyme |
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| Mol. Mass.: | 37557.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Purchased from Calbiochem (San Diego, CA). |
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| Residue: | 333 |
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| Sequence: | MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
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| BDBM56911 |
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| n/a |
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| Name | BDBM56911 |
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| Synonyms: | 2-(1-methyl-6-oxidanyl-4-oxidanylidene-pyrimidin-2-yl)sulfanyl-N-naphthalen-1-yl-ethanamide | 2-(6-hydroxy-1-methyl-4-oxopyrimidin-2-yl)sulfanyl-N-naphthalen-1-ylacetamide | 2-[(6-hydroxy-1-methyl-4-oxo-2-pyrimidinyl)thio]-N-(1-naphthalenyl)acetamide | 2-[(6-hydroxy-4-keto-1-methyl-pyrimidin-2-yl)thio]-N-(1-naphthyl)acetamide | MLS000078330 | SMR000039918 | cid_658924 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H15N3O3S |
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| Mol. Mass. | 341.384 |
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| SMILES | Cn1c(SCC(=O)Nc2cccc3ccccc23)nc(O)cc1=O |
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| Structure | 
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