| Reaction Details |
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 | Report a problem with these data |
| Target | Procathepsin L |
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| Ligand | BDBM59951 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for inhibitors of M1 and M17 aminopeptidases: QFRET-based biochemical high throughput dose response assay for inhibitors of the Cathepsin L proteinase (CTSL1). |
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| IC50 | 59331±n/a nM |
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| Citation |  PubChem, PC Counterscreen for inhibitors of M1 and M17 aminopeptidases: QFRET-based biochemical high throughput dose response assay for inhibitors of the Cathepsin L proteinase (CTSL1). PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Procathepsin L |
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| Name: | Procathepsin L |
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| Synonyms: | CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein |
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| Type: | Enzyme |
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| Mol. Mass.: | 37557.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Purchased from Calbiochem (San Diego, CA). |
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| Residue: | 333 |
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| Sequence: | MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
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| BDBM59951 |
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| n/a |
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| Name | BDBM59951 |
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| Synonyms: | 4,5-Dimethoxy-2-[2-(3,5,8-trimethyl-quinolin-2-ylsulfanyl)-acetylamino]-benzoic acid | 4,5-dimethoxy-2-[2-(3,5,8-trimethylquinolin-2-yl)sulfanylethanoylamino]benzoic acid | 4,5-dimethoxy-2-[[1-oxo-2-[(3,5,8-trimethyl-2-quinolinyl)thio]ethyl]amino]benzoic acid | 4,5-dimethoxy-2-[[2-(3,5,8-trimethylquinolin-2-yl)sulfanylacetyl]amino]benzoic acid | 4,5-dimethoxy-2-[[2-[(3,5,8-trimethyl-2-quinolyl)thio]acetyl]amino]benzoic acid | MLS000548308 | SMR000170972 | cid_1176185 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H24N2O5S |
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| Mol. Mass. | 440.512 |
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| SMILES | COc1cc(NC(=O)CSc2nc3c(C)ccc(C)c3cc2C)c(cc1OC)C(O)=O |
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| Structure | 
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