| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Bcl-2-like protein 1 |
|---|
| Ligand | BDBM53342 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Counterscreen for inhibitors of MCL1: fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of BCL2-related protein, long isoform (BCLXL). |
|---|
| IC50 | 37072±n/a nM |
|---|
| Citation |  PubChem, PC Counterscreen for inhibitors of MCL1: fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of BCL2-related protein, long isoform (BCLXL). PubChem Bioassay(2009)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Bcl-2-like protein 1 |
|---|
| Name: | Bcl-2-like protein 1 |
|---|
| Synonyms: | Anti-apoptotic Bcl-2 protein | Apoptosis Regulator Bcl-xL | Apoptosis regulator Bcl-X | B2CL1_HUMAN | BCL2-like 1 isoform 1 | BCL2L | BCL2L1 | BCLX | Bcl-2-like protein 1 (Bcl-XL) | Bcl-X | Bcl-xL/Bcl-2-binding component 3 | Bcl2-L-1 | Bcl2-antagonist of cell death (BAD) |
|---|
| Type: | Mitochondrion membrane; Single-pass membrane protein |
|---|
| Mol. Mass.: | 26039.60 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 233 |
|---|
| Sequence: | MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLA
DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY
QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEP
WIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK
|
|
|
|---|
| BDBM53342 |
|---|
| n/a |
|---|
| Name | BDBM53342 |
|---|
| Synonyms: | (E)-3-(2-furanyl)-N-[2-oxo-2-[(2-oxo-3-indolyl)hydrazo]ethyl]-2-propenamide | (E)-3-(2-furyl)-N-[2-keto-2-[N'-(2-ketoindol-3-yl)hydrazino]ethyl]acrylamide | (E)-3-(furan-2-yl)-N-[2-oxidanylidene-2-[2-(2-oxidanylideneindol-3-yl)hydrazinyl]ethyl]prop-2-enamide | (E)-3-(furan-2-yl)-N-[2-oxo-2-[2-(2-oxoindol-3-yl)hydrazinyl]ethyl]prop-2-enamide | MLS001075666 | SMR000646156 | cid_5900936 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H14N4O4 |
|---|
| Mol. Mass. | 338.3175 |
|---|
| SMILES | O=C(CNC(=O)\C=C\c1ccco1)NNC1=c2ccccc2=NC1=O |c:16,23| |
|---|
| Structure | 
|
|---|
Search and Browse
