Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fibroblast growth factor receptor 4 | ||
| Ligand | BDBM102217 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | FGFR-4 wild type assay at Km | ||
| pH | 7.5±n/a | ||
| Temperature | 298.15±n/a K | ||
| IC50 | <10.00±n/a nM | ||
| Comments | extracted | ||
| Citation |  Bifulco, Jr., N; DiPietro, LV; Miduturu, CV Inhibitors of the fibroblast growth factor receptor US Patent US9695165 Publication Date 7/4/2017 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fibroblast growth factor receptor 4 | |||
| Name: | Fibroblast growth factor receptor 4 | ||
| Synonyms: | CD_antigen: CD334 FGFR4 | FGFR-4 | FGFR4 | FGFR4_HUMAN | Fibroblast growth factor receptor | Fibroblast growth factor receptor 4 (FGFR4) | JK2 | JTK2 | TKF | ||
| Type: | Protein | ||
| Mol. Mass.: | 87957.45 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P22455 | ||
| Residue: | 802 | ||
| Sequence: |
| ||
| BDBM102217 | |||
| n/a | |||
| Name | BDBM102217 | ||
| Synonyms: | US9695165, 19 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H23Cl2N3O4 | ||
| Mol. Mass. | 524.395 | ||
| SMILES | CCn1c2cc(ncc2cc(-c2c(Cl)c(OC)cc(OC)c2Cl)c1=O)-c1ccccc1NC(=O)C=C |(-6,-.38,;-4.67,-1.15,;-3.33,-.38,;-2,-1.15,;-2,-2.69,;-.67,-3.47,;.67,-2.69,;.67,-1.15,;-.67,-.38,;-.67,1.15,;-2,1.93,;-2,3.47,;-.67,4.23,;.67,3.47,;-.67,5.78,;.67,6.54,;2,5.78,;-2,6.54,;-3.33,5.78,;-4.67,6.54,;-4.67,8.08,;-3.33,4.23,;-4.67,3.47,;-3.33,1.15,;-4.67,1.93,;-.67,-5,;-2,-5.78,;-2,-7.31,;-.67,-8.08,;.67,-7.31,;.67,-5.78,;2,-5,;3.33,-5.77,;3.33,-7.31,;4.67,-5,;6,-5.77,)| | ||
| Structure | 
| ||