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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fibroblast growth factor receptor 4 | ||
| Ligand | BDBM103870 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | FGFR-4 wild type assay at Km | ||
| pH | 7.5±n/a | ||
| Temperature | 298.15±n/a K | ||
| IC50 | <10.00±n/a nM | ||
| Comments | extracted | ||
| Citation |  Bifulco, Jr., N; DiPietro, LV; Miduturu, CV Inhibitors of the fibroblast growth factor receptor US Patent US9695165 Publication Date 7/4/2017 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fibroblast growth factor receptor 4 | |||
| Name: | Fibroblast growth factor receptor 4 | ||
| Synonyms: | CD_antigen: CD334 FGFR4 | FGFR-4 | FGFR4 | FGFR4_HUMAN | Fibroblast growth factor receptor | Fibroblast growth factor receptor 4 (FGFR4) | JK2 | JTK2 | TKF | ||
| Type: | Protein | ||
| Mol. Mass.: | 87957.45 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P22455 | ||
| Residue: | 802 | ||
| Sequence: |
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| BDBM103870 | |||
| n/a | |||
| Name | BDBM103870 | ||
| Synonyms: | US9695165, 53 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C30H26Cl2FN3O5 | ||
| Mol. Mass. | 598.449 | ||
| SMILES | CCn1c2cc(ncc2cc(-c2c(Cl)c(OC)cc(OC)c2Cl)c1=O)-c1cc2N(C(C)COc2cc1F)C(=O)C=C |(3.33,.77,;2,,;.67,.77,;-.67,,;-.67,-1.54,;-2,-2.31,;-3.33,-1.54,;-3.33,,;-2,.77,;-2,2.31,;-.67,3.08,;-.67,4.62,;-2,5.39,;-3.33,4.62,;-2,6.93,;-3.33,7.7,;-4.67,6.93,;-.67,7.7,;.67,6.93,;2,7.7,;2,9.24,;.67,5.39,;2,4.62,;.67,2.31,;2,3.08,;-2,-3.85,;-.67,-4.62,;-.67,-6.16,;.67,-6.93,;.67,-8.47,;2,-9.24,;-.67,-9.24,;-2,-8.47,;-2,-6.93,;-3.33,-6.16,;-3.33,-4.62,;-4.67,-3.85,;2,-6.16,;2,-4.62,;3.33,-6.93,;4.67,-6.16,)| | ||
| Structure | 
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