| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM54805 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SAR analysis of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay |
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| IC50 | 1150±n/a nM |
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| Citation |  PubChem, PC SAR analysis of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42648.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41145 |
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| Residue: | 380 |
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| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
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|
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| BDBM54805 |
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| n/a |
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| Name | BDBM54805 |
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| Synonyms: | (phenylmethyl) N-[1-[[2,6-bis(chloranyl)phenyl]carbamothioylamino]-2,2,2-tris(chloranyl)ethyl]carbamate | MLS000561692 | N-[2,2,2-trichloro-1-[(2,6-dichlorophenyl)thiocarbamoylamino]ethyl]carbamic acid benzyl ester | N-[2,2,2-trichloro-1-[[(2,6-dichloroanilino)-sulfanylidenemethyl]amino]ethyl]carbamic acid (phenylmethyl) ester | SMR000173875 | benzyl N-[2,2,2-trichloro-1-[(2,6-dichlorophenyl)carbamothioylamino]ethyl]carbamate | cid_3091265 | {2,2,2-Trichloro-1-[3-(2,6-dichloro-phenyl)-thioureido]-ethyl}-carbamic acid benzyl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C17H14Cl5N3O2S |
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| Mol. Mass. | 501.642 |
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| SMILES | Clc1cccc(Cl)c1NC(=S)NC(NC(=O)OCc1ccccc1)C(Cl)(Cl)Cl |
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| Structure | 
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