| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM40197 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SAR analysis of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay |
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| IC50 | 8770±n/a nM |
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| Citation |  PubChem, PC SAR analysis of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42648.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41145 |
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| Residue: | 380 |
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| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
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| BDBM40197 |
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| n/a |
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| Name | BDBM40197 |
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| Synonyms: | (2Z)-2-[(8-quinolinylamino)methylidene]-1-benzothiophen-3-one | (2Z)-2-[(8-quinolylamino)methylene]benzothiophen-3-one | (2Z)-2-[(quinolin-8-ylamino)methylidene]-1-benzothiophen-3-one | 2-[(8-quinolinylamino)methylene]-1-benzothiophen-3(2H)-one | MLS000530291 | SMR000135268 | cid_5407397 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H12N2OS |
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| Mol. Mass. | 304.366 |
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| SMILES | Oc1c(C=Nc2cccc3cccnc23)sc2ccccc12 |w:4.4| |
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| Structure | 
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