| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
|---|
| Ligand | BDBM62200 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | SAR analysis of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay |
|---|
| IC50 | 10000±n/a nM |
|---|
| Citation |  PubChem, PC SAR analysis of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Kappa-type opioid receptor |
|---|
| Name: | Kappa-type opioid receptor |
|---|
| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 42648.76 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P41145 |
|---|
| Residue: | 380 |
|---|
| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
|
|
|
|---|
| BDBM62200 |
|---|
| n/a |
|---|
| Name | BDBM62200 |
|---|
| Synonyms: | 4-[[(4-methoxyphenyl)sulfonylamino]methyl]-N-[2-[methyl-(phenylmethyl)amino]ethyl]benzamide | MLS-0425701.0001 | N-[2-[benzyl(methyl)amino]ethyl]-4-[[(4-methoxyphenyl)sulfonylamino]methyl]benzamide | cid_20854195 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H29N3O4S |
|---|
| Mol. Mass. | 467.58 |
|---|
| SMILES | COc1ccc(cc1)S(=O)(=O)NCc1ccc(cc1)C(=O)NCCN(C)Cc1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
