| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM62178 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SAR analysis of Antagonists of the Kappa Opioid Receptor (KOR) using an Image-Based Assay |
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| IC50 | 32000±n/a nM |
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| Citation |  PubChem, PC SAR analysis of Antagonists of the Kappa Opioid Receptor (KOR) using an Image-Based Assay PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42648.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41145 |
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| Residue: | 380 |
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| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
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|
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| BDBM62178 |
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| n/a |
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| Name | BDBM62178 |
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| Synonyms: | MLS-0019234.0001 | N-[(2-keto-6-methyl-1H-quinolin-3-yl)methyl]-N-methyl-picolinamide | N-methyl-N-[(6-methyl-2-oxidanylidene-1H-quinolin-3-yl)methyl]pyridine-2-carboxamide | N-methyl-N-[(6-methyl-2-oxo-1H-quinolin-3-yl)methyl]-2-pyridinecarboxamide | N-methyl-N-[(6-methyl-2-oxo-1H-quinolin-3-yl)methyl]pyridine-2-carboxamide | cid_665054 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H17N3O2 |
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| Mol. Mass. | 307.3465 |
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| SMILES | CN(Cc1cc2cc(C)ccc2[nH]c1=O)C(=O)c1ccccn1 |
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| Structure | 
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