| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM62207 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SAR analysis of Antagonists of the Kappa Opioid Receptor (KOR) using an Image-Based Assay |
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| IC50 | 32000±n/a nM |
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| Citation |  PubChem, PC SAR analysis of Antagonists of the Kappa Opioid Receptor (KOR) using an Image-Based Assay PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42648.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41145 |
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| Residue: | 380 |
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| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
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|
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| BDBM62207 |
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| n/a |
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| Name | BDBM62207 |
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| Synonyms: | MLS-0362777.0001 | cid_24791925 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H34N6O2 |
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| Mol. Mass. | 486.6086 |
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| SMILES | Cc1ccc(C)c(c1)N1CCN(CCCNC(=O)CCn2c3ncccc3n3cccc3c2=O)CC1 |
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| Structure | 
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