Reaction Details |
| Report a problem with these data |
Target | Sphingosine 1-phosphate receptor 5 |
---|
Ligand | BDBM62394 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | Late stage counterscreen assay for S1P4 antagonists: Fluorescence dose response cell-based screening assay for antagonists of the Sphingosine 1-Phosphate Receptor 5 (S1P5) |
---|
IC50 | >25000±n/a nM |
---|
Citation | PubChem, PC Late stage counterscreen assay for S1P4 antagonists: Fluorescence dose response cell-based screening assay for antagonists of the Sphingosine 1-Phosphate Receptor 5 (S1P5) PubChem Bioassay(2010)[AID] |
---|
More Info.: | Get all data from this article, Solution Info, Assay Method |
---|
|
Sphingosine 1-phosphate receptor 5 |
---|
Name: | Sphingosine 1-phosphate receptor 5 |
Synonyms: | EDG8 | Endothelial differentiation sphingolipid G-protein-coupled receptor 8 | S1P5 | S1PR5 | S1PR5_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-8 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 41796.42 |
Organism: | Homo sapiens (Human) |
Description: | n/a |
Residue: | 398 |
Sequence: | MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLV
LGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALT
ASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLD
ACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRA
RRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSL
LNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSF
SGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD
|
|
|
BDBM62394 |
---|
n/a |
---|
Name | BDBM62394 |
Synonyms: | 5-(2,5-difluorophenyl)-N-(2,6-dimethylphenyl)-2-furamide | 5-(2,5-difluorophenyl)-N-(2,6-dimethylphenyl)-2-furancarboxamide | 5-(2,5-difluorophenyl)-N-(2,6-dimethylphenyl)furan-2-carboxamide | 5-[2,5-bis(fluoranyl)phenyl]-N-(2,6-dimethylphenyl)furan-2-carboxamide | SR-02000000238 | SR-02000000238-1 | cid_44607573 |
Type | Small organic molecule |
Emp. Form. | C19H15F2NO2 |
Mol. Mass. | 327.3247 |
SMILES | Cc1cccc(C)c1NC(=O)c1ccc(o1)-c1cc(F)ccc1F |
Structure |
|