Reaction Details |
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Target | Sphingosine 1-phosphate receptor 5 |
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Ligand | BDBM62396 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Late stage counterscreen assay for S1P4 antagonists: Fluorescence dose response cell-based screening assay for antagonists of the Sphingosine 1-Phosphate Receptor 5 (S1P5) |
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IC50 | >25000±n/a nM |
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Citation | PubChem, PC Late stage counterscreen assay for S1P4 antagonists: Fluorescence dose response cell-based screening assay for antagonists of the Sphingosine 1-Phosphate Receptor 5 (S1P5) PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Sphingosine 1-phosphate receptor 5 |
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Name: | Sphingosine 1-phosphate receptor 5 |
Synonyms: | EDG8 | Endothelial differentiation sphingolipid G-protein-coupled receptor 8 | S1P5 | S1PR5 | S1PR5_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-8 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 41796.42 |
Organism: | Homo sapiens (Human) |
Description: | n/a |
Residue: | 398 |
Sequence: | MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLV
LGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALT
ASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLD
ACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRA
RRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSL
LNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSF
SGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD
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BDBM62396 |
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n/a |
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Name | BDBM62396 |
Synonyms: | N-(2,6-dimethylphenyl)-5-(4-methyl-3-thienyl)-2-furamide | N-(2,6-dimethylphenyl)-5-(4-methyl-3-thiophenyl)-2-furancarboxamide | N-(2,6-dimethylphenyl)-5-(4-methylthiophen-3-yl)furan-2-carboxamide | SR-02000000240 | SR-02000000240-1 | cid_44607581 |
Type | Small organic molecule |
Emp. Form. | C18H17NO2S |
Mol. Mass. | 311.398 |
SMILES | Cc1cscc1-c1ccc(o1)C(=O)Nc1c(C)cccc1C |
Structure |
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