| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM54778 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SAR Analysis of Antagonists of the DOR Receptor using an Image-Based Assay |
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| IC50 | 32000±n/a nM |
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| Citation |  PubChem, PC SAR Analysis of Antagonists of the DOR Receptor using an Image-Based Assay PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40382.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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| BDBM54778 |
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| n/a |
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| Name | BDBM54778 |
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| Synonyms: | 2-[4-(2-furanylmethyl)-5-[[(E)-3-phenylprop-2-enyl]thio]-1,2,4-triazol-3-yl]pyridine | 2-[4-(furan-2-ylmethyl)-5-[(E)-3-phenylprop-2-enyl]sulfanyl-1,2,4-triazol-3-yl]pyridine | 2-[5-[[(E)-cinnamyl]thio]-4-(2-furfuryl)-1,2,4-triazol-3-yl]pyridine | 2-{4-(2-furylmethyl)-5-[(3-phenyl-2-propen-1-yl)thio]-4H-1,2,4-triazol-3-yl}pyridine | MLS000065151 | SMR000078652 | cid_1982054 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H18N4OS |
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| Mol. Mass. | 374.459 |
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| SMILES | C(Sc1nnc(-c2ccccn2)n1Cc1ccco1)\C=C\c1ccccc1 |
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| Structure | 
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