Reaction Details |
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Target | Delta-type opioid receptor |
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Ligand | BDBM62183 |
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Substrate/Competitor | n/a |
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Meas. Tech. | SAR Analysis of Antagonists of the DOR Receptor using an Image-Based Assay |
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IC50 | 32000±n/a nM |
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Citation | PubChem, PC SAR Analysis of Antagonists of the DOR Receptor using an Image-Based Assay PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Delta-type opioid receptor |
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Name: | Delta-type opioid receptor |
Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 40382.98 |
Organism: | Homo sapiens (Human) |
Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
Residue: | 372 |
Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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BDBM62183 |
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n/a |
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Name | BDBM62183 |
Synonyms: | MLS-0425691.0001 | [1-[[1-(m-tolyl)imidazol-2-yl]methyl]-4-p-anisyl-4-piperidyl]methanol | [4-[(4-methoxyphenyl)methyl]-1-[[1-(3-methylphenyl)-2-imidazolyl]methyl]-4-piperidinyl]methanol | [4-[(4-methoxyphenyl)methyl]-1-[[1-(3-methylphenyl)imidazol-2-yl]methyl]piperidin-4-yl]methanol | cid_44537712 |
Type | Small organic molecule |
Emp. Form. | C25H31N3O2 |
Mol. Mass. | 405.5325 |
SMILES | COc1ccc(CC2(CO)CCN(Cc3nccn3-c3cccc(C)c3)CC2)cc1 |
Structure |
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