| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Delta-type opioid receptor |
|---|
| Ligand | BDBM62201 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | SAR Analysis of Antagonists of the DOR Receptor using an Image-Based Assay |
|---|
| IC50 | 32000±n/a nM |
|---|
| Citation |  PubChem, PC SAR Analysis of Antagonists of the DOR Receptor using an Image-Based Assay PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Delta-type opioid receptor |
|---|
| Name: | Delta-type opioid receptor |
|---|
| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 40382.98 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
|---|
| Residue: | 372 |
|---|
| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
|
|
|
|---|
| BDBM62201 |
|---|
| n/a |
|---|
| Name | BDBM62201 |
|---|
| Synonyms: | 4-methoxy-N-[[4-[4-(phenylmethyl)piperazin-1-yl]carbonylphenyl]methyl]benzenesulfonamide | 4-methoxy-N-[[4-[oxo-[4-(phenylmethyl)-1-piperazinyl]methyl]phenyl]methyl]benzenesulfonamide | MLS-0364353.0001 | N-[4-(4-benzylpiperazine-1-carbonyl)benzyl]-4-methoxy-benzenesulfonamide | N-[[4-(4-benzylpiperazine-1-carbonyl)phenyl]methyl]-4-methoxybenzenesulfonamide | cid_20854208 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H29N3O4S |
|---|
| Mol. Mass. | 479.591 |
|---|
| SMILES | COc1ccc(cc1)S(=O)(=O)NCc1ccc(cc1)C(=O)N1CCN(Cc2ccccc2)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
