| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM62204 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SAR Analysis of Antagonists of the DOR Receptor using an Image-Based Assay |
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| IC50 | 32000±n/a nM |
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| Citation |  PubChem, PC SAR Analysis of Antagonists of the DOR Receptor using an Image-Based Assay PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40382.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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|
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| BDBM62204 |
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| n/a |
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| Name | BDBM62204 |
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| Synonyms: | MLS-0360688.0001 | N-[3-[4-(4-fluorophenyl)-1-piperazinyl]propyl]-2-(4-oxo-5-pyrrolo[1,2-a]quinoxalinyl)acetamide | N-[3-[4-(4-fluorophenyl)piperazin-1-yl]propyl]-2-(4-oxidanylidenepyrrolo[1,2-a]quinoxalin-5-yl)ethanamide | N-[3-[4-(4-fluorophenyl)piperazin-1-yl]propyl]-2-(4-oxopyrrolo[1,2-a]quinoxalin-5-yl)acetamide | N-[3-[4-(4-fluorophenyl)piperazino]propyl]-2-(4-ketopyrrolo[1,2-a]quinoxalin-5-yl)acetamide | cid_22522555 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H28FN5O2 |
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| Mol. Mass. | 461.5312 |
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| SMILES | Fc1ccc(cc1)N1CCN(CCCNC(=O)Cn2c3ccccc3n3cccc3c2=O)CC1 |
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| Structure | 
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