Reaction Details |
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Target | Delta-type opioid receptor |
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Ligand | BDBM62190 |
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Substrate/Competitor | n/a |
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Meas. Tech. | SAR Analysis of Agonists of the DOR Receptor using an Image-Based Assay |
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EC50 | >32000±n/a nM |
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Citation | PubChem, PC SAR Analysis of Agonists of the DOR Receptor using an Image-Based Assay PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Delta-type opioid receptor |
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Name: | Delta-type opioid receptor |
Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 40382.98 |
Organism: | Homo sapiens (Human) |
Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
Residue: | 372 |
Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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BDBM62190 |
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n/a |
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Name | BDBM62190 |
Synonyms: | 4-[[(4-acetylphenyl)sulfonylamino]methyl]-N-[2-(3-fluoroanilino)-2-keto-ethyl]-N-methyl-benzamide | 4-[[(4-acetylphenyl)sulfonylamino]methyl]-N-[2-(3-fluoroanilino)-2-oxoethyl]-N-methylbenzamide | 4-[[(4-ethanoylphenyl)sulfonylamino]methyl]-N-[2-[(3-fluorophenyl)amino]-2-oxidanylidene-ethyl]-N-methyl-benzamide | MLS-0332830.0001 | cid_16295215 |
Type | Small organic molecule |
Emp. Form. | C25H24FN3O5S |
Mol. Mass. | 497.539 |
SMILES | CN(CC(=O)Nc1cccc(F)c1)C(=O)c1ccc(CNS(=O)(=O)c2ccc(cc2)C(C)=O)cc1 |
Structure |
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