| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit |
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| Ligand | BDBM64775 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for inhibitors of PP5: fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 1 (PP1) |
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| IC50 | 67047±n/a nM |
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| Citation |  PubChem, PC Counterscreen for inhibitors of PP5: fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 1 (PP1) PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Serine/threonine-protein phosphatase PP1-alpha catalytic subunit |
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| Name: | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit |
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| Synonyms: | PP-1A | PP1A_HUMAN | PPP1A | PPP1CA | Serine/threonine protein phosphatase PP1-alpha catalytic subunit | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit | protein phosphatase 1, catalytic subunit, alpha isoform 3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 37510.66 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_197827 |
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| Residue: | 330 |
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| Sequence: | MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
KNKGKYGQFSGLNPGGRPITPPRNSAKAKK
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| BDBM64775 |
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| n/a |
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| Name | BDBM64775 |
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| Synonyms: | 5-Amino-4-oxo-3-p-tolyl-3,4-dihydro-thieno[3,4-d]pyridazine-1-carboxylic acid ethyl ester | 5-amino-3-(4-methylphenyl)-4-oxo-1-thieno[3,4-d]pyridazinecarboxylic acid ethyl ester | 5-amino-4-keto-3-(p-tolyl)thieno[3,4-d]pyridazine-1-carboxylic acid ethyl ester | MLS000528230 | SMR000120805 | cid_3153302 | ethyl 5-amino-3-(4-methylphenyl)-4-oxothieno[3,4-d]pyridazine-1-carboxylate | ethyl 5-azanyl-3-(4-methylphenyl)-4-oxidanylidene-thieno[3,4-d]pyridazine-1-carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C16H15N3O3S |
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| Mol. Mass. | 329.374 |
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| SMILES | CCOC(=O)c1nn(-c2ccc(C)cc2)c(=O)c2c(N)scc12 |
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| Structure | 
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