Ki Summary

Reaction Details

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Target

Trans-activator protein BZLF1

Ligand

BDBM64849

Substrate/Competitor

n/a

Meas. Tech.

Counterscreen for inhibitors of PP1: fluorescence-based biochemical high throughput dose response assay to identify inhibitors of Protein Phosphatase 5 (PP5)

IC50

>67047±n/a nM

Citation

PubChem, PC Counterscreen for inhibitors of PP1: fluorescence-based biochemical high throughput dose response assay to identify inhibitors of Protein Phosphatase 5 (PP5) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Trans-activator protein BZLF1

Name:

Trans-activator protein BZLF1

Synonyms:

BZLF1 | BZLF1_EBVB9 | PPP5C protein

Type:

Enzyme Catalytic Domain

Mol. Mass.:

26856.37

Organism:

Human herpesvirus 4

Description:

gi_82503229

Residue:

245

Sequence:

MMDPNSTSEDVKFTPDPYQVPFVQAFDQATRVYQDLGGPSQAPLPCVLWPVLPEPLPQGQ
LTAYHVSTAPTGSWFSAPQPAPENAYQAYAAPQLFPVSDITQNQQTNQAGGEAPQPGDNS
TVQTAAAVVFACPGANQGQQLADIGVPQPAPVAAPARRTRKPQQPESLEECDSELEIKRY
KNRVASRKCRAKFKQLLQHYREVAAAKSSENDRLRLLLKQMCPSLDVDSIIPRTPDVLHE
DLLNF

BDBM64849

n/a

Name

BDBM64849

Synonyms:

1-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-keto-N-[4-(2-pyridyl)thiazol-2-yl]pyrrolidine-3-carboxamide | 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-oxidanylidene-N-(4-pyridin-2-yl-1,3-thiazol-2-yl)pyrrolidine-3-carboxamide | 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-oxo-N-(4-pyridin-2-yl-1,3-thiazol-2-yl)pyrrolidine-3-carboxamide | 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-oxo-N-[4-(2-pyridinyl)-2-thiazolyl]-3-pyrrolidinecarboxamide | MLS000394395 | SMR000261836 | cid_5033819

Type

Small organic molecule

Emp. Form.

C21H18N4O4S

Mol. Mass.

422.457

SMILES

O=C(Nc1nc(cs1)-c1ccccn1)C1CN(C(=O)C1)c1ccc2OCCOc2c1

Structure