| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Tumor necrosis factor |
|---|
| Ligand | BDBM54386 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | HTS dose response assay for identification of inhibitors of TNFa-specific NF-kB induction |
|---|
| IC50 | 6825±1127.5 nM |
|---|
| Citation |  PubChem, PC HTS dose response assay for identification of inhibitors of TNFa-specific NF-kB induction PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Tumor necrosis factor |
|---|
| Name: | Tumor necrosis factor |
|---|
| Synonyms: | Cachectin | TNF | TNF-a | TNF-alpha | TNFA | TNFA_HUMAN | TNFSF2 | Tumor necrosis factor (TNF-alpha) | Tumor necrosis factor (TNFa) | Tumor necrosis factor alpha (TNFα) | Tumor necrosis factor ligand superfamily member 2 | Tumor necrosis factor, membrane form | Tumor necrosis factor, soluble form | tumor necrosis factor alpha |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 25645.11 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P01375 |
|---|
| Residue: | 233 |
|---|
| Sequence: | MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQR
EEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELR
DNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRE
TPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL
|
|
|
|---|
| BDBM54386 |
|---|
| n/a |
|---|
| Name | BDBM54386 |
|---|
| Synonyms: | 1-hydroxy-N-(3-nitrophenyl)-2-naphthalenecarboxamide | 1-hydroxy-N-(3-nitrophenyl)-2-naphthamide | 1-hydroxy-N-(3-nitrophenyl)naphthalene-2-carboxamide | MLS000736670 | N-(3-nitrophenyl)-1-oxidanyl-naphthalene-2-carboxamide | SMR000528239 | cid_242249 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H12N2O4 |
|---|
| Mol. Mass. | 308.2882 |
|---|
| SMILES | Oc1c(ccc2ccccc12)C(=O)Nc1cccc(c1)[N+]([O-])=O |
|---|
| Structure | 
|
|---|
Search and Browse
