| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM66107 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput counterscreen to identify inhibitors of TEM-1 metallo-beta-lactamase |
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| IC50 | 26747±n/a nM |
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| Citation |  PubChem, PC Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput counterscreen to identify inhibitors of TEM-1 metallo-beta-lactamase PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | n/a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 29494.42 |
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| Organism: | Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67 |
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| Description: | gi_60115532 |
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| Residue: | 269 |
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| Sequence: | MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRP
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
RGIIAALGPDGKPSRIVVIYTDGESGNYG
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|
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| BDBM66107 |
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| n/a |
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| Name | BDBM66107 |
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| Synonyms: | 7-(diethylamino)-2-keto-chromene-3-carbaldehyde | 7-(diethylamino)-2-oxidanylidene-chromene-3-carbaldehyde | 7-(diethylamino)-2-oxo-1-benzopyran-3-carboxaldehyde | 7-(diethylamino)-2-oxochromene-3-carbaldehyde | 7-Diethylamino-2-oxo-2H-chromene-3-carbaldehyde | MLS000529175 | SMR000121650 | cid_143191 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H15NO3 |
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| Mol. Mass. | 245.2738 |
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| SMILES | CCN(CC)c1ccc2cc(C=O)c(=O)oc2c1 |
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| Structure | 
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