| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM66116 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput counterscreen to identify inhibitors of TEM-1 metallo-beta-lactamase |
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| IC50 | 1225±n/a nM |
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| Citation |  PubChem, PC Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput counterscreen to identify inhibitors of TEM-1 metallo-beta-lactamase PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | n/a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 29494.42 |
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| Organism: | Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67 |
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| Description: | gi_60115532 |
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| Residue: | 269 |
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| Sequence: | MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRP
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
RGIIAALGPDGKPSRIVVIYTDGESGNYG
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|
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| BDBM66116 |
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| n/a |
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| Name | BDBM66116 |
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| Synonyms: | 2-(7-piperidin-1-yl-4,4a,5,6-tetrahydro-3H-naphthalen-2-ylidene)propanedinitrile | 2-(7-piperidino-4,4a,5,6-tetrahydro-3H-naphthalen-2-ylidene)malononitrile | 2-[7-(1-piperidinyl)-4,4a,5,6-tetrahydro-3H-naphthalen-2-ylidene]propanedinitrile | MLS000392804 | SMR000261727 | cid_3517787 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H21N3 |
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| Mol. Mass. | 279.3794 |
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| SMILES | N#C\[#6](C#N)=[#6]-1/[#6]-[#6]-[#6]-2-[#6]-[#6]-[#6](=[#6]-[#6]-2=[#6]-1)-[#7]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1 |c:11,14| |
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| Structure | 
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