| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM66148 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput counterscreen to identify inhibitors of TEM-1 metallo-beta-lactamase |
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| IC50 | >59640±n/a nM |
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| Citation |  PubChem, PC Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput counterscreen to identify inhibitors of TEM-1 metallo-beta-lactamase PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | n/a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 29494.42 |
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| Organism: | Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67 |
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| Description: | gi_60115532 |
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| Residue: | 269 |
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| Sequence: | MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRP
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
RGIIAALGPDGKPSRIVVIYTDGESGNYG
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|
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| BDBM66148 |
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| n/a |
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| Name | BDBM66148 |
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| Synonyms: | MLS001224570 | N-[(E)-1-[4-(p-anisoylamino)phenyl]ethylideneamino]isonicotinamide | N-[1-[4-(p-anisoylamino)phenyl]ethylideneamino]isonicotinamide | N-[1-[4-[(4-methoxybenzoyl)amino]phenyl]ethylideneamino]pyridine-4-carboxamide | N-[1-[4-[(4-methoxyphenyl)carbonylamino]phenyl]ethylideneamino]pyridine-4-carboxamide | N-[1-[4-[[(4-methoxyphenyl)-oxomethyl]amino]phenyl]ethylideneamino]-4-pyridinecarboxamide | SMR000679031 | cid_4299664 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H20N4O3 |
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| Mol. Mass. | 388.4192 |
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| SMILES | COc1ccc(cc1)C(=O)Nc1ccc(cc1)C(C)=NNC(=O)c1ccncc1 |w:19.21| |
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| Structure | 
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