| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM66149 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput counterscreen to identify inhibitors of TEM-1 metallo-beta-lactamase |
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| IC50 | 28143±n/a nM |
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| Citation |  PubChem, PC Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput counterscreen to identify inhibitors of TEM-1 metallo-beta-lactamase PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | n/a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 29494.42 |
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| Organism: | Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67 |
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| Description: | gi_60115532 |
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| Residue: | 269 |
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| Sequence: | MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRP
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
RGIIAALGPDGKPSRIVVIYTDGESGNYG
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|
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| BDBM66149 |
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| n/a |
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| Name | BDBM66149 |
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| Synonyms: | 2-azanylidene-7-(diethylamino)-N-[(4-fluorophenyl)methyl]chromene-3-carboxamide | 7-(diethylamino)-N-(4-fluorobenzyl)-2-imino-chromene-3-carboxamide | 7-(diethylamino)-N-[(4-fluorophenyl)methyl]-2-imino-1-benzopyran-3-carboxamide | 7-(diethylamino)-N-[(4-fluorophenyl)methyl]-2-iminochromene-3-carboxamide | MLS001229989 | SMR000678657 | cid_19289050 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H22FN3O2 |
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| Mol. Mass. | 367.4167 |
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| SMILES | CCN(CC)c1ccc2cc(C(=O)NCc3ccc(F)cc3)c(=N)oc2c1 |
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| Structure | 
|
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