Reaction Details |
![](/images/Email.png) | Report a problem with these data |
Target | Beta-lactamase |
---|
Ligand | BDBM66134 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase |
---|
IC50 | 8927±n/a nM |
---|
Citation | PubChem, PC Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase PubChem Bioassay(2010)[AID] |
---|
More Info.: | Get all data from this article, Solution Info, Assay Method |
---|
|
Beta-lactamase |
---|
Name: | Beta-lactamase |
Synonyms: | Beta-lactamase | metallo-beta-lactamase IMP-1 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 27125.88 |
Organism: | Pseudomonas aeruginosa |
Description: | gi_27368096 |
Residue: | 246 |
Sequence: | MSKLSVFFIFLFCSIATAAESLPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNA
EAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELT
NELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKP
YGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESKK
PSKPSN
|
|
|
BDBM66134 |
---|
n/a |
---|
Name | BDBM66134 |
Synonyms: | 2-[(1,1-diketo-1,2-benzothiazol-3-yl)-[[4-(dimethylamino)benzylidene]amino]amino]ethanol | 2-[[1,1-bis(oxidanylidene)-1,2-benzothiazol-3-yl]-[[4-(dimethylamino)phenyl]methylideneamino]amino]ethanol | 2-[[[4-(dimethylamino)phenyl]methylideneamino]-(1,1-dioxo-1,2-benzothiazol-3-yl)amino]ethanol | 4-(dimethylamino)benzaldehyde (1,1-dioxido-1,2-benzisothiazol-3-yl)(2-hydroxyethyl)hydrazone | MLS001196408 | SMR000556211 | cid_4002873 |
Type | Small organic molecule |
Emp. Form. | C18H20N4O3S |
Mol. Mass. | 372.441 |
SMILES | CN(C)c1ccc(C=NN(CCO)C2=NS(=O)(=O)c3ccccc23)cc1 |t:13| |
Structure |
|