Ki Summary

Reaction Details

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Target

Bcl-2-like protein 11

Ligand

BDBM67054

Substrate/Competitor

n/a

Meas. Tech.

Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis

EC50

>350000±n/a nM

Citation

PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Bcl-2-like protein 11

Name:

Bcl-2-like protein 11

Synonyms:

B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM

Type:

PROTEIN

Mol. Mass.:

22175.26

Organism:

Homo sapiens (Human)

Description:

EBI_101325

Residue:

198

Sequence:

MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSP
QGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPP
CQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPR
MVILRLLRYIVRLVWRMH

BDBM67054

n/a

Name

BDBM67054

Synonyms:

(2R)-2-allylsuccinic acid O1-[(2S)-2-[[(2S)-2-[2-[[(1R)-1-benzyl-2-hydroxy-ethyl]amino]-2-keto-ethyl]pent-4-enoyl]amino]-3-phenyl-propyl] ester O4-tert-butyl ester | (2R)-2-prop-2-enylbutanedioic acid O4-tert-butyl ester O1-[(2S)-2-[[(2S)-2-[2-[[(2R)-1-hydroxy-3-phenylpropan-2-yl]amino]-2-oxoethyl]-1-oxopent-4-enyl]amino]-3-phenylpropyl] ester | 4-O-tert-butyl 1-O-[(2S)-2-[[(2S)-2-[2-[[(2R)-1-hydroxy-3-phenylpropan-2-yl]amino]-2-oxoethyl]pent-4-enoyl]amino]-3-phenylpropyl] (2R)-2-prop-2-enylbutanedioate | MLS002320301 | O4-tert-butyl O1-[(2S)-2-[[(2S)-2-[2-oxidanylidene-2-[[(2R)-1-oxidanyl-3-phenyl-propan-2-yl]amino]ethyl]pent-4-enoyl]amino]-3-phenyl-propyl] (2R)-2-prop-2-enylbutanedioate | SMR001337926 | cid_44201802

Type

Small organic molecule

Emp. Form.

C36H48N2O7

Mol. Mass.

620.7755

SMILES

CC(C)(C)OC(=O)C[C@@H](CC=C)C(=O)OC[C@H](Cc1ccccc1)NC(=O)[C@@H](CC=C)CC(=O)N[C@@H](CO)Cc1ccccc1

Structure