| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Nucleotide-binding oligomerization domain-containing protein 1 |
|---|
| Ligand | BDBM65737 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | SAR analysis of compounds that inhibit NOD1 - Set 3 |
|---|
| IC50 | >20000±n/a nM |
|---|
| Citation |  PubChem, PC SAR analysis of compounds that inhibit NOD1 - Set 3 PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Nucleotide-binding oligomerization domain-containing protein 1 |
|---|
| Name: | Nucleotide-binding oligomerization domain-containing protein 1 |
|---|
| Synonyms: | CARD4 | NOD1 | NOD1_HUMAN | nucleotide-binding oligomerization domain containing 1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 107699.03 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_5174617 |
|---|
| Residue: | 953 |
|---|
| Sequence: | MEEQGHSEMEIIPSESHPHIQLLKSNRELLVTHIRNTQCLVDNLLKNDYFSAEDAEIVCA
CPTQPDKVRKILDLVQSKGEEVSEFFLYLLQQLADAYVDLRPWLLEIGFSPSLLTQSKVV
VNTDPVSRYTQQLRHHLGRDSKFVLCYAQKEELLLEEIYMDTIMELVGFSNESLGSLNSL
ACLLDHTTGILNEQGETIFILGDAGVGKSMLLQRLQSLWATGRLDAGVKFFFHFRCRMFS
CFKESDRLCLQDLLFKHYCYPERDPEEVFAFLLRFPHVALFTFDGLDELHSDLDLSRVPD
SSCPWEPAHPLVLLANLLSGKLLKGASKLLTARTGIEVPRQFLRKKVLLRGFSPSHLRAY
ARRMFPERALQDRLLSQLEANPNLCSLCSVPLFCWIIFRCFQHFRAAFEGSPQLPDCTMT
LTDVFLLVTEVHLNRMQPSSLVQRNTRSPVETLHAGRDTLCSLGQVAHRGMEKSLFVFTQ
EEVQASGLQERDMQLGFLRALPELGPGGDQQSYEFFHLTLQAFFTAFFLVLDDRVGTQEL
LRFFQEWMPPAGAATTSCYPPFLPFQCLQGSGPAREDLFKNKDHFQFTNLFLCGLLSKAK
QKLLRHLVPAAALRRKRKALWAHLFSSLRGYLKSLPRVQVESFNQVQAMPTFIWMLRCIY
ETQSQKVGQLAARGICANYLKLTYCNACSADCSALSFVLHHFPKRLALDLDNNNLNDYGV
RELQPCFSRLTVLRLSVNQITDGGVKVLSEELTKYKIVTYLGLYNNQITDVGARYVTKIL
DECKGLTHLKLGKNKITSEGGKYLALAVKNSKSISEVGMWGNQVGDEGAKAFAEALRNHP
SLTTLSLASNGISTEGGKSLARALQQNTSLEILWLTQNELNDEVAESLAEMLKVNQTLKH
LWLIQNQITAKGTAQLADALQSNTGITEICLNGNLIKPEEAKVYEDEKRIICF
|
|
|
|---|
| BDBM65737 |
|---|
| n/a |
|---|
| Name | BDBM65737 |
|---|
| Synonyms: | 3-methyl-8-(3-phenylpropylsulfanyl)-7-propan-2-yl-purine-2,6-dione | 3-methyl-8-(3-phenylpropylsulfanyl)-7-propan-2-ylpurine-2,6-dione | 3-methyl-8-(3-phenylpropylthio)-7-propan-2-ylpurine-2,6-dione | 7-isopropyl-3-methyl-8-(3-phenylpropylthio)xanthine | MLS-0059529.0001 | cid_3111693 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H22N4O2S |
|---|
| Mol. Mass. | 358.458 |
|---|
| SMILES | CC(C)n1c(SCCCc2ccccc2)nc2n(C)c(=O)[nH]c(=O)c12 |
|---|
| Structure | 
|
|---|
Search and Browse
