| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Tumor necrosis factor |
|---|
| Ligand | BDBM62307 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SAR analysis of inhibitors of TNFa specific NF-kB induction - Set 3 |
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| IC50 | >20000±n/a nM |
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| Citation |  PubChem, PC SAR analysis of inhibitors of TNFa specific NF-kB induction - Set 3 PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Tumor necrosis factor |
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| Name: | Tumor necrosis factor |
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| Synonyms: | Cachectin | TNF | TNF-a | TNF-alpha | TNFA | TNFA_HUMAN | TNFSF2 | Tumor necrosis factor (TNF-alpha) | Tumor necrosis factor (TNFa) | Tumor necrosis factor alpha (TNFα) | Tumor necrosis factor ligand superfamily member 2 | Tumor necrosis factor, membrane form | Tumor necrosis factor, soluble form | tumor necrosis factor alpha |
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| Type: | Enzyme |
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| Mol. Mass.: | 25645.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P01375 |
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| Residue: | 233 |
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| Sequence: | MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQR
EEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELR
DNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRE
TPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL
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|
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| BDBM62307 |
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| n/a |
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| Name | BDBM62307 |
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| Synonyms: | (5,6-dimethyl-1-tosyl-benzimidazol-2-yl)amine | 5,6-dimethyl-1-(4-methylphenyl)sulfonyl-2-benzimidazolamine | 5,6-dimethyl-1-(4-methylphenyl)sulfonyl-benzimidazol-2-amine | 5,6-dimethyl-1-(4-methylphenyl)sulfonylbenzimidazol-2-amine | MLS-0425618.0001 | cid_44229067 |
|---|
| Type | Small organic molecule |
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| Emp. Form. | C16H17N3O2S |
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| Mol. Mass. | 315.39 |
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| SMILES | Cc1ccc(cc1)S(=O)(=O)n1c(N)nc2cc(C)c(C)cc12 |
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| Structure | 
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