| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Tumor necrosis factor |
|---|
| Ligand | BDBM67406 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | SAR analysis of inhibitors of TNFa specific NF-kB induction - Set 3 |
|---|
| IC50 | >20000±n/a nM |
|---|
| Citation |  PubChem, PC SAR analysis of inhibitors of TNFa specific NF-kB induction - Set 3 PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Tumor necrosis factor |
|---|
| Name: | Tumor necrosis factor |
|---|
| Synonyms: | Cachectin | TNF | TNF-a | TNF-alpha | TNFA | TNFA_HUMAN | TNFSF2 | Tumor necrosis factor (TNF-alpha) | Tumor necrosis factor (TNFa) | Tumor necrosis factor alpha (TNFα) | Tumor necrosis factor ligand superfamily member 2 | Tumor necrosis factor, membrane form | Tumor necrosis factor, soluble form | tumor necrosis factor alpha |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 25645.11 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P01375 |
|---|
| Residue: | 233 |
|---|
| Sequence: | MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQR
EEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELR
DNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRE
TPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL
|
|
|
|---|
| BDBM67406 |
|---|
| n/a |
|---|
| Name | BDBM67406 |
|---|
| Synonyms: | 1-(4-fluorophenyl)sulfonyl-2-benzimidazolamine | 1-(4-fluorophenyl)sulfonylbenzimidazol-2-amine | MLS-0435750.0001 | [1-(4-fluorophenyl)sulfonylbenzimidazol-2-yl]amine | cid_45253891 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H10FN3O2S |
|---|
| Mol. Mass. | 291.301 |
|---|
| SMILES | Nc1nc2ccccc2n1S(=O)(=O)c1ccc(F)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
